BDBM50469347 CHEMBL4287078

SMILES CCC(C)CNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1

InChI Key InChIKey=YTOQTXOTRNNBQW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469347   

TargetTyrosine-protein kinase Mer(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469347(CHEMBL4287078)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469347(CHEMBL4287078)
Affinity DataIC50: 12nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469347(CHEMBL4287078)
Affinity DataIC50: 100nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Unc Eshelman School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469347(CHEMBL4287078)
Affinity DataIC50: 37nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed