BDBM50469207 CHEMBL4281099

SMILES Oc1ccc(cc1)S(=O)(=O)NCCNc1nccc(n1)-c1c(nc2sccn12)-c1ccc(F)cc1

InChI Key InChIKey=PBLFUUIJXILSEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469207   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469207(CHEMBL4281099)
Affinity DataIC50: 19nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
University of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469207(CHEMBL4281099)
Affinity DataIC50: 40nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed