BDBM50469189 CHEMBL4284209

SMILES CC(C)c1cnn2c(NCc3ccc(cc3)-c3ccccn3)nc(N[C@H]3CC[C@H](N)CC3)nc12

InChI Key InChIKey=PRJNNPMIUGYOST-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50469189   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Mouse)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human CDK2/cyclin A after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins in presence of [gamma-33P] by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant GST-tagged human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant GST-tagged human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 320nMAssay Description:Inhibition of porcine brain GSK3 using GS-1 as substrate after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant GST-tagged human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK2(Mouse)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Poitiers

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant GST-tagged human DYRK2 expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 130nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50469189(CHEMBL4284209)
Affinity DataIC50: 89nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed