BDBM50469180 CHEMBL4292755

SMILES CN1CCN(CC1)c1ccc2c(Nc3cc(C)[nH]n3)nc(nc2c1)-c1ccccc1

InChI Key InChIKey=GBMDFZRFAMTRLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50469180   

TargetAurora kinase B(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50469180(CHEMBL4292755)
Affinity DataIC50: 270nMAssay Description:Inhibition of Aurora B (unknown origin) using FAM-labelled peptide as substrate pretreated for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50469180(CHEMBL4292755)
Affinity DataIC50: 10nMAssay Description:Inhibition of Aurora A (unknown origin) using FAM-labelled peptide as substrate pretreated for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50469180(CHEMBL4292755)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human Aurora A (1 to 403 residues) expressed in Escherichia coli using FAM-labeled peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed