BDBM50468898 CHEMBL4278309

SMILES CCCCCC(=O)N[C@@H]([C@H](O)C(C)C)C(=O)O[C@H](C(C)C)[C@@H]1NC(=O)[C@H](C)N(C)C(=O)[C@H](C)NC(=O)C(=C)N(C)C(=O)[C@@H](Cc2ccccc2)OC(=O)[C@@H](NC(C)=O)[C@@H](C)OC(=O)[C@H]([C@@H](C)OC)N(C)C1=O

InChI Key InChIKey=OIXFCGWUWTUMJO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50468898   

LigandPNGBDBM50468898(CHEMBL4278309)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Gs coupled adrenergic beta2 receptor in HEK293 cells assessed as reduction in isoproterenol-induced cAMP production pretreated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein subunit alpha-11(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468898(CHEMBL4278309)
Affinity DataIC50: 891nMAssay Description:Inhibition of recombinant human Gq/11 coupled N-terminal 3His-tagged M1 receptor expressed in CHOK1 cells assessed as reduction in carbachol-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein subunit alpha-11(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468898(CHEMBL4278309)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant human Gq/11 coupled N-terminal 3His-tagged M1 receptor expressed in CHOK1 cells assessed as reduction in carbachol-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGuanine nucleotide-binding protein G(o) subunit alpha(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50468898(CHEMBL4278309)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed