BDBM50468632 CHEMBL4293491

SMILES CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)n1nc(C)c(Cl)c1C

InChI Key InChIKey=RFAYOJJBVSPOFY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50468632   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468632(CHEMBL4293491)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human NPP1 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468632(CHEMBL4293491)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human NPP3 expressed in COS7 cells using p-nitrophenyl-5'-thymidine monophosphate as substrate preincubated for 5 to 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468632(CHEMBL4293491)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human TNAP expressed in COS7 cells using CDP-star as substrate preincubated for 5 to 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468632(CHEMBL4293491)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human IAP expressed in COS7 cells using CDP-star as substrate preincubated for 5 to 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Rat)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50468632(CHEMBL4293491)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rat NTPDase1 expressed in CHO cells using ATP as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed