BDBM50468563 CHEMBL4276699

SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccc2OCCOc2c1)C(=S)Nc1ccccc1

InChI Key InChIKey=HOLWDHRFWFZKMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468563   

TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468563(CHEMBL4276699)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468563(CHEMBL4276699)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed