BDBM50468495 CHEMBL4280835

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc2c(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)ncnc2s1

InChI Key InChIKey=XQNBRKJAXBTZMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468495   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468495(CHEMBL4280835)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 (679 to 1255 residues) expressed in baculovirus infected Sf9 cells using Poly-(Glu, Tyr) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468495(CHEMBL4280835)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human C-terminal His-tagged/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed