BDBM50468442 CHEMBL4276759::US10968163, Compound 4a

SMILES COc1cc(ccc1O)[C@H]1[C@@H]([C@@H]([C@H]1C(=O)Oc1cccc2ccccc12)c1ccc(O)c(OC)c1)C(O)=O

InChI Key InChIKey=ULSDOUSGHGOKSJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50468442   

TargetFatty acid-binding protein, heart(Human)
The State University of New York

US Patent
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi:  190nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetFatty acid-binding protein, brain(Human)
The State University of New York

US Patent
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi:  190nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetFatty acid-binding protein, heart(Human)
The State University of New York

US Patent
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP3 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFatty acid-binding protein, brain(Human)
The State University of New York

US Patent
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi:  2.12E+3nMAssay Description:Displacement of ANS from recombinant human N-terminal His-tagged FABP7 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of DAUDA from recombinant human N-terminal His-tagged FABP5 expressed in Escherichia coli BL21(DE3) after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFatty acid-binding protein 5(Human)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50468442(CHEMBL4276759 | US10968163, Compound 4a)
Affinity DataKi: >1.00E+7nMAssay Description:FABP5 was purified and delipidated as described previously (Kaczocha, M. et al. 2012). FABP5 (30 μg), NBD-stearate (1 μM), and a competitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent