BDBM50468395 CHEMBL4294625

SMILES CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(cc4)C4CCN(CCO)CC4)c3)c(OCCO)cc12

InChI Key InChIKey=XSFHSBDHUMMKQC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50468395   

TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50468395(CHEMBL4294625)
Affinity DataIC50: 16nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 (790 to 1356 residues) cytoplasmic domain expressed in baculovirus expression system after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50468395(CHEMBL4294625)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR3 (436 to 806 residues) cytoplasmic domain expressed in baculovirus expression system after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50468395(CHEMBL4294625)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR2 (399 to 821 residues) cytoplasmic domain expressed in baculovirus expression system after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50468395(CHEMBL4294625)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR1 (398 to 822 residues) cytoplasmic domain expressed in baculovirus expression system after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed