BDBM50468316 CHEMBL4280893

SMILES CCCN1CC(=O)N2Cc3c(CC2C1=O)c1ccccc1n3Cc1ccc(cc1)C(=O)NO

InChI Key InChIKey=WKWJMPGMWAQUAL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50468316   

TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant HDAC6 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of human recombinant HDAC1 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic trifluoroacetyl lysine as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of human recombinant HDAC10 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 747nMAssay Description:Inhibition of human recombinant HDAC8 using RHKAcKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of human recombinant HDAC2 using RHKKAcAMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50468316(CHEMBL4280893)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed