BDBM50468261 Tyrphostin Ag 879::Tyrphostin Ag-879

SMILES CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C

InChI Key InChIKey=XRZYELWZLNAXGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468261   

TargetEphrin type-A receptor 3(Mouse)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50468261(Tyrphostin Ag 879 | Tyrphostin Ag-879)
Affinity DataIC50: 5nMAssay Description:Inhibition of ETK phosphorylation in mouse RAS-3T3 cells incubated for 1 hr by immunoblotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50468261(Tyrphostin Ag 879 | Tyrphostin Ag-879)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HER2/ErbB-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Complutense University of Madrid

Curated by ChEMBL
LigandPNGBDBM50468261(Tyrphostin Ag 879 | Tyrphostin Ag-879)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TrKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed