BDBM50468250 CHEMBL4286029

SMILES Fc1ccc(NC(=O)c2sccc2Nc2cccc3OCCOc23)cc1

InChI Key InChIKey=PMUBRDNCIWKVPM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468250   

TargetVascular endothelial growth factor receptor 1(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468250(CHEMBL4286029)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) using KKKSPGEYVNIEFG substrate and [33P-g-ATP] incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Kwazulu Natal

Curated by ChEMBL
LigandPNGBDBM50468250(CHEMBL4286029)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR1 (unknown origin) using KKKSPGEYVNIEFG as substrate at 2 uM by [gamma-33P]ATP based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
National Institute of Pharmaceutical Education and Research-Hyderabad

Curated by ChEMBL
LigandPNGBDBM50468250(CHEMBL4286029)
Affinity DataEC50:  3.50E+4nMAssay Description:Inhibition of ABCB1 efflux pump in human LS180 cells using Rh123 as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed