BDBM50468208 CHEMBL4278812

SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccc(O)cc1

InChI Key InChIKey=PHXSLQUXNZUSIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468208   

TargetTyrosine-protein kinase ABL1(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50468208(CHEMBL4278812)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50468208(CHEMBL4278812)
Affinity DataIC50: 341nMAssay Description:Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468208(CHEMBL4278812)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed