BDBM50468205 CHEMBL4277755

SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccc1C#N)-c1ccncc1

InChI Key InChIKey=QRJCQQTTXWLPAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468205   

LigandPNGBDBM50468205(CHEMBL4277755)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Mouse)
Palack£

Curated by ChEMBL
LigandPNGBDBM50468205(CHEMBL4277755)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50468205(CHEMBL4277755)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed