BDBM50468138 CHEMBL4292738

SMILES CC1(C)CCc2cccc(CN3CCC4(CN(C(=O)O4)c4ccc(cc4)C(O)=O)CC3)c2O1

InChI Key InChIKey=JJHUPQVQOKRLAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468138   

TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468138(CHEMBL4292738)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468138(CHEMBL4292738)
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468138(CHEMBL4292738)
Affinity DataIC50: 399nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed