BDBM50468129 CHEMBL4288848

SMILES CCOc1cc(CN2CCC(COc3cccc4cccnc34)CC2)cc(OCC)c1-c1ccc(F)cc1

InChI Key InChIKey=FUSKAZYRYKJDCI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50468129   

TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50: 0.600nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50: 2.90nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50: 210nMAssay Description:Inhibition of MK-499 binding to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed