BDBM50467926 CHEMBL4290759

SMILES COc1cc2CCN(CCCCNC(=O)c3ccc(cc3)C#N)Cc2cc1O

InChI Key InChIKey=YBSUKYVKWAEWJF-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467926   

TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50467926(CHEMBL4290759)
Affinity DataEC50:  1.40E+3nMAssay Description:Antagonist activity at human dopamine D3 receptor assessed as inhibition of beta-arrestin recruitment by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50467926(CHEMBL4290759)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]N-Methylspiperone from human dopamine D3 receptor expressed in HEKT cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50467926(CHEMBL4290759)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-methylspiperone from dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50467926(CHEMBL4290759)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]DTG from sigma2 receptor(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed