BDBM50467912 CHEMBL4293700

SMILES Nc1nc2cc(ccc2c2[nH]c(CN3CCCC3=O)nc12)-c1ccccc1

InChI Key InChIKey=SUBWHJLGYZCPRD-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467912   

TargetToll-like receptor 8(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50467912(CHEMBL4293700)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TLR8 (unknown origin) expressed in HEK-Blue cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50467912(CHEMBL4293700)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human NLRP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50467912(CHEMBL4293700)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TLR7 (unknown origin) expressed in HEK-Blue cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed