BDBM50467871 CHEMBL4288538

SMILES Clc1ccccc1-c1nnc(SC2=CS(=O)(=O)c3ccccc23)o1

InChI Key InChIKey=BRKWENIVBVBFMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467871   

TargetInosine-5'-monophosphate dehydrogenase(Cryptococcus neoformans var. neoformans serotype D...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467871(CHEMBL4288538)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467871(CHEMBL4288538)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH1 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467871(CHEMBL4288538)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH2 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed