BDBM50467867 CHEMBL4288980

SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2cccnc2)c2ccccc12

InChI Key InChIKey=USFCTVBCGHNOJC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467867   

TargetInosine-5'-monophosphate dehydrogenase(Cryptococcus neoformans var. neoformans serotype D...)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467867(CHEMBL4288980)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467867(CHEMBL4288980)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH1 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50467867(CHEMBL4288980)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH2 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed