BDBM50467508 CHEMBL4284580

SMILES OC(=O)\C=C\c1ccc2occ(C(=O)Nc3ccccc3)c(=O)c2c1

InChI Key InChIKey=DLWNTPFPPXXHTP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467508   

TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50467508(CHEMBL4284580)
Affinity DataIC50: 4.66E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decrease in H2O2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50467508(CHEMBL4284580)
Affinity DataIC50: 9.25E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured after 5 mins by El...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM50467508(CHEMBL4284580)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1 using rhodamine-EVNLDAEFK-quencher as substrate after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed