BDBM50467504 CHEMBL4288354

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(CC)C2=O)c1ccc(Br)s1

InChI Key InChIKey=VJRFKHSBKSOGIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467504   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467504(CHEMBL4288354)
Affinity DataIC50: 160nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467504(CHEMBL4288354)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE5A using FL-cGMP as substrate incubated for 1.5 hrs by IMAP-fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed