BDBM50467489 CHEMBL4292970

SMILES CCc1ccc(o1)C1N(CC(=O)c2c1[nH]c1ccccc21)c1ncc(cn1)-c1ccc(OC)c(OC)c1

InChI Key InChIKey=MXRCTQYKTXQWTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467489   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467489(CHEMBL4292970)
Affinity DataIC50: 634nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467489(CHEMBL4292970)
Affinity DataIC50: 288nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE6C expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467489(CHEMBL4292970)
Affinity DataIC50: 53nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-GMP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed