BDBM50467476 CHEMBL4280648

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(CCCC)C2=O)c1ccc(CC)s1

InChI Key InChIKey=MHKSTLAWFJQTLC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50467476   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PDE2A (2 to 941 residues) expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE3B (592 to end residues) expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE4A1A expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 107nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE6C expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-GMP as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467476(CHEMBL4280648)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE1A expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed