BDBM50467389 CHEMBL4295113

SMILES C#CCNc1nc(NCCCC2CCN(Cc3ccccc3)CC2)c(cc1C#N)C#N

InChI Key InChIKey=QDTPLCGSZPKZME-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50467389   

TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467389(CHEMBL4295113)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of recombinant human MAOB using tyramine hydrochloride as substrate preincubated for 30 mins followed by substrate addition measured for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467389(CHEMBL4295113)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467389(CHEMBL4295113)
Affinity DataIC50: 600nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50467389(CHEMBL4295113)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human MAOA using tyramine hydrochloride as substrate preincubated for 30 mins followed by substrate addition measured for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed