BDBM50467372 CHEMBL4293467

SMILES CSc1ncc2c(Nc3n[nH]c(C)c3N=C2c2ccccc2C(F)(F)F)n1

InChI Key InChIKey=IDMDQNLKWPITHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467372   

TargetAurora kinase A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467372(CHEMBL4293467)
Affinity DataIC50: 128nMAssay Description:Inhibition of Aurora A (unknown origin) using STK S2 as substrate after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467372(CHEMBL4293467)
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467372(CHEMBL4293467)
Affinity DataIC50: 307nMAssay Description:Inhibition of Aurora B (unknown origin) using STK S2 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed