BDBM50467275 CHEMBL4279457

SMILES COc1cc2c(Oc3ccc(NC(=O)c4cc5cccnc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=LODWOBAYUQRWKD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50467275   

TargetALK tyrosine kinase receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 200nMAssay Description:Inhibition of ALK (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of c-MET (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 183nMAssay Description:Inhibition of FLT4 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of FLT3 (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50467275(CHEMBL4279457)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-KIT (unknown origin) using FAM-labeled peptide as substrate incubated for 10 mins followed by substrate addition by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed