BDBM50467225 CHEMBL4286267

SMILES CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c1cc(Cl)cc(Cl)c1)C(=O)OCC1CCN(CC1)C(=O)OC(C)(C)C

InChI Key InChIKey=OXOWIXRLBXHEJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467225   

TargetNeurogenic locus notch homolog protein 1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50467225(CHEMBL4286267)
Affinity DataIC50: 640nMAssay Description:Inhibition of Notch1 deltaE mutant (unknown origin) expressed in HEK293 cells after 16 hrs by resazurin dye-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed