BDBM50467205 CHEMBL4281213

SMILES CN1C(=O)C(Cc2ccc(Cl)cc2)=C(c2c[nH]c3cc(Cl)ccc23)[C@]1(O)Cc1ccc(Cl)cc1

InChI Key InChIKey=HHGSWONIEYVVCX-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467205   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Jss Academy of Higher Education and Research

Curated by ChEMBL
LigandPNGBDBM50467205(CHEMBL4281213)
Affinity DataKd:  500nMAssay Description:Binding affinity to recombinant human MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in tryptophan fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed