BDBM50467204 CHEMBL2381406

SMILES CCOc1cc(ccc1C2=N[C@H]([C@H](N2C(=O)N3CCN(CC3)CCO)c4ccc(cc4)Br)c5ccc(cc5)Br)OC

InChI Key InChIKey=PVRYEWOXWGDQHA-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467204   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Jss Academy of Higher Education and Research

Curated by ChEMBL
LigandPNGBDBM50467204(CHEMBL2381406)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)