BDBM50467089 CHEMBL4295161

SMILES NCC(=O)Nc1ccc(Oc2ccc3n(CC4CC4)c(N)c(C#N)c3c2)cc1

InChI Key InChIKey=MLJKHSWYZHQWGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467089   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetArsenite methyltransferase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed