BDBM50467088 CHEMBL4280063

SMILES Nc1[nH]c2ccc(OCc3ccccc3)cc2c1C#N

InChI Key InChIKey=PAOATYUTLBQHTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467088   

TargetArsenite methyltransferase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed