BDBM50466862 CHEMBL270722

SMILES CC1=CC(=O)Oc2c1cc3ccc(c(c3c2)[N+](=O)[O-])O

InChI Key InChIKey=LDFBABFNEAVJKG-UHFFFAOYSA-N

Data  1 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50466862   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human GST-fused DYRK1A expressed in Escherichia coli BL21 (DE3) using DYRKtide as substrate after 10 mins in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha/beta(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat liver CK2 using RRRADDSDDDDD as substrate after 10 mins in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat liver CK2 phosphorylation using RRRADDSDDDDD as substrate in presence of [32p]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 340nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 340nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50466862(CHEMBL270722)
Affinity DataKi:  220nMAssay Description:Inhibition of rat liver CK2 phosphorylation using RRRADDSDDDDD as substrate in presence of [32p]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed