BDBM50466852 CHEMBL4294976

SMILES CCOc1ccccc1CNc1nc(C)nc2[nH]cc(-c3ccnc(N)c3)c12

InChI Key InChIKey=JCJWCXBSDFGDSJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466852   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466852(CHEMBL4294976)
Affinity DataIC50: 8nMAssay Description:Inhibition of human full-length N-terminal GST-tagged DYRK1B (1 to 629 residues) expressed in baculovirus expression system using MBP as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466852(CHEMBL4294976)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human full-length N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in baculovirus expression system using MBP as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466852(CHEMBL4294976)
Affinity DataIC50: 10nMAssay Description:Inhibition of human full-length N-terminal GST-fused CDK9 (1 to 372 residues) expressed in baculovirus expression system using MBP as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed