BDBM50466687 CHEMBL4291468

SMILES COc1cccc(c1)C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1

InChI Key InChIKey=YAUMOGALQJYOJQ-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50466687   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 1.81E+4nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataEC50:  961nMAssay Description:Transactivation of GAL4-DBD fused human PPARgamma ligand binding domain expressed in UAS-bla HEL 293H cells preincubated for 16 hrs followed by FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitochondrial pyruvate carrier 2(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
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Curated by ChEMBL
LigandPNGBDBM50466687(CHEMBL4291468)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed