BDBM50466581 CHEMBL4288154

SMILES Cn1c2ccc(cc2c(=O)n(C)c1=O)S(=O)(=O)NC1CC1

InChI Key InChIKey=ZYHBAVPJYZASEO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466581   

TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Manchester

Curated by ChEMBL

LigandBDBM50466581(CHEMBL4288154)Copy SMILESCopy InChI

Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Jiangnan University

Curated by ChEMBL

LigandBDBM50466581(CHEMBL4288154)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) preincubated for 10 mins followed by ATP addition and measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL