BDBM50466577 CHEMBL4284056

SMILES CC1(CC1)NS(=O)(=O)c1ccc2C(=O)c3ccccc3C(=O)c2c1

InChI Key InChIKey=ZKZUGMQSWLZLLI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466577   

TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50466577(CHEMBL4284056)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of human full length PARG using Bt-NAD ribosylated PARP1 substrate after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPoly(ADP-ribose) glycohydrolase(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50466577(CHEMBL4284056)
Affinity DataEC50:  6.60E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed