BDBM50466394 CHEMBL4285809

SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3c(Br)cnc4[nH]cnc34)c(F)c2)c1=O

InChI Key InChIKey=LHGBMCHXJSBVDX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466394   

TargetTyrosine-protein kinase Mer(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed