BDBM50466379 CHEMBL4292660

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(C)(C)C(=O)N2CC3(CCC3)C2)cc1

InChI Key InChIKey=SLDVOINBPKMOPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466379   

TargetNuclear receptor ROR-gamma(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466379(CHEMBL4292660)
Affinity DataIC50: 1.00E+4nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466379(CHEMBL4292660)
Affinity DataIC50: 470nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466379(CHEMBL4292660)
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]-Digoxin from recombinant human GST-fused RORgammat LBD after 1 to 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed