BDBM50466376 CHEMBL4293421

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(C)(C)C(=O)Nc2cc(F)ccn2)cc1

InChI Key InChIKey=DZNYPAHRQMSYIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466376   

TargetNuclear receptor ROR-gamma(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466376(CHEMBL4293421)
Affinity DataIC50: 31nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Mouse)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466376(CHEMBL4293421)
Affinity DataIC50: 320nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed