BDBM50465991 CHEMBL4277615

SMILES [H][C@]1(OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CNC(=O)CCCCNC(=O)c1ccc(NC(C)=O)cc1

InChI Key InChIKey=SRCDNXUBIYWHLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465991   

TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465991(CHEMBL4277615)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465991(CHEMBL4277615)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465991(CHEMBL4277615)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465991(CHEMBL4277615)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed