BDBM50465965 CHEMBL4277834

SMILES [H][C@]1(OC(=C[C@H](O)[C@H]1NC(=O)CC)C(O)=O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=QOEZQHJNDYABPZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465965   

TargetSialidase-1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465965(CHEMBL4277834)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-4(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465965(CHEMBL4277834)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-3(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465965(CHEMBL4277834)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSialidase-2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50465965(CHEMBL4277834)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed