BDBM50465913 CHEMBL4278935

SMILES Oc1cc(ccc1-c1ccc(OC2CCNCC2(F)F)nn1)-n1cccn1

InChI Key InChIKey=FJJWYYDKYYXUFG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50465913   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50465913(CHEMBL4278935)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in CHO cell membranes after 90 mins by micro-beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSurvival motor neuron protein(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50465913(CHEMBL4278935)
Affinity DataEC50:  3.30E+3nMAssay Description:Modulation of human SMN2 level in NSC34 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50465913(CHEMBL4278935)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed