BDBM50465912 CHEMBL4287623

SMILES [#8]C1([#6]-[#6]-[#7](-[#6]-[#6]-[#6]\[#6]=[#6](/c2ccc(F)cc2)-c2ccc(F)cc2)-[#6]-[#6]1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=MZVVLAMPOFUDJD-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50465912   

TargetD(2) dopamine receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  317nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in stable fibroblast cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  328nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  526nMAssay Description:Displacement of [3H]Cimetidine from human H2 receptor expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  552nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293T cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  718nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]-Way100635 from human 5HT1A receptor expressed in stable CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2C receptor expressed in HEK293FlpIN cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50465912(CHEMBL4287623)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT7A receptor expressed in HEK cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed