BDBM50465795 CHEMBL4285527

SMILES COc1ccccc1-n1nc(cc1-c1ccc(Cl)cc1)[C@@H]1CCO[C@@H](C1)C(C)C

InChI Key InChIKey=VTJFSPOVFGEZFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465795   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50465795(CHEMBL4285527)
Affinity DataIC50: 7nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50465795(CHEMBL4285527)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed