BDBM50465754 CHEMBL4293890

SMILES CN(C)Cc1ccc(cc1)-c1ccc(NCCCN2CCCCC2)c(OCCN2CCCCC2)c1

InChI Key InChIKey=XZPGJRJXFPHTDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465754   

TargetBeta-secretase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50465754(CHEMBL4293890)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells harboring wild type APP695 assessed as reduction in amyloid beta (1 to 42) level after 24 hrs by ELISA met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50465754(CHEMBL4293890)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells harboring wild type APP695 assessed as reduction in amyloid beta (1 to 40) level after 24 hrs by ELISA met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed