BDBM50465752 CHEMBL4281647

SMILES COc1ccc([C@H](CC2CC2)NC(=O)N(C)C2CCN(CC2)C2CCc3cc(ccc23)-c2cc(C)ncn2)c(Cl)c1Cl

InChI Key InChIKey=YTCAYOLJCRJYCL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465752   

TargetGrowth hormone secretagogue receptor type 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50465752(CHEMBL4281647)
Affinity DataEC50:  439nMAssay Description:Inverse agonist at recombinant human GHSR1a expressed in HEK293 cells assessed as decrease in IP1 accumulation after 1 hr by IP1-d2-based HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50465752(CHEMBL4281647)
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at recombinant human GHSR1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced intracellular calcium release inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed