BDBM50465750 CHEMBL4292914

SMILES C[C@H](NC(=O)N(C)C1CCN(CC1)C1CCc2cc(C)ccc12)c1ccc(C#CC2CC2)c(Cl)c1Cl

InChI Key InChIKey=KOOYRHMXKJUKGV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465750   

TargetGrowth hormone secretagogue receptor type 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50465750(CHEMBL4292914)
Affinity DataIC50: 282nMAssay Description:Antagonist activity at recombinant human GHSR1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced intracellular calcium release inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Sib Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50465750(CHEMBL4292914)
Affinity DataEC50:  117nMAssay Description:Inverse agonist at recombinant human GHSR1a expressed in HEK293 cells assessed as decrease in IP1 accumulation after 1 hr by IP1-d2-based HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed