BDBM50465611 CHEMBL4284808

SMILES C(Cc1c[nH]c2ccccc12)N(CC1CCCCC1)Cc1ccccc1

InChI Key InChIKey=JUELMOYHZBVAKK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465611   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
University of Salerno

Curated by ChEMBL

LigandBDBM50465611(CHEMBL4284808)Copy SMILESCopy InChI

Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced channel currents by whole cell patch clamp methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
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TargetTransient receptor potential cation channel subfamily M member 8(Rat)
University of Salerno

Curated by ChEMBL

LigandBDBM50465611(CHEMBL4284808)Copy SMILESCopy InChI

Affinity DataIC50: 600nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as reduction in menthol-induced calcium flux incubated for 60 mins by Fluo-4 NW-d...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL